Product Formula
PD Balance consists of two complementary daily pouches, each targeting different aspects of Parkinson's disease pathology.
PD Balance 1
10g daily on empty stomach | Energy Metabolism & Fat-Soluble Delivery
This pouch uses supercritical CO₂-extracted marula oil in a liposomal powder matrix to enhance bioavailability of lipophilic compounds. It synergizes to support oxidative stress reduction, membrane stabilization, microbiome health, and energy production.
35-45% / Marula Oil Powder
Our 100% organic oil is rich in oleic acid (approximately 78%), tocopherols, and phytosterols. In 2025, animal Parkinson's Disease (PD) models demonstrated that these components provide dopaminergic neuron protection and improve motor performance. Specifically, they stabilize mitochondrial membranes and improve complex I activity, which is the complex most vulnerable in PD. Phytosterols and tocopherols also reduce lipid peroxidation in neuronal membranes, potentially slowing α-synuclein aggregation. The MarulaLab oil nanoemulsion has been shown to reduce brain MDA levels and restore glutathione levels, effectively quenching reactive oxygen species and protecting dopaminergic neurons. Furthermore, our liposomal powder technology enhances the absorption and bioavailability of active ingredients, further protecting dopaminergic neurons and improving motor performance by reducing oxidative stress. This makes it a foundational neuroprotective agent that may slow α-synuclein aggregation. We have also observed marked reductions in key drivers of PD-related neuroinflammation, including TNF-α, IL-1β, and microglial activation. Finally, our organic sourcing contributes to these anti-inflammatory benefits and overall cellular resilience in PD.
3-8% / Sunflower Lecithin
5% purity plant-source phosphatidylcholine. Supports neuronal phospholipid homeostasis and the dispersion of lipophilic nutrients for brain cell stability. PC is the dominant phospholipid in neuronal plasma, mitochondrial, and ER membranes. PD brains show lower PC content and altered fatty acid composition. Oral PC can be remodelled in the brain to restore membrane integrity. As a choline reservoir, it supports the cholinergic anti-inflammatory reflex on microglia and macrophages, offering potential benefits for cognitive and motor function in PD patients.
1-3% / Licorice Extract
99% purity ammonium glycyrrhizate. Modulates cortisol metabolism and neuroinflammation, easing stress-related PD symptoms. combined with stem cells, synergistically clears damaged mitochondria, reversing the neurotoxicity of MPTP (a neurotoxin that destroys dopaminergic neurons in the brain). Contains a natural compound that helps protect dopamine by blocking an enzyme (called MAO-B) that usually breaks down dopamine. The purified extract helps balance inflammatory responses and maintain neuronal stability in the management of PD.
0.3-0.5% / Vitamin B1 (Thiamine)
99% pure Thiamine (vitamin B1) may benefit coping with Parkinson’s disease by supporting neuronal energy metabolism and modulating dopaminergic function. PD brains show reduced activity of thiamine-dependent enzymes (e.g., α-ketoglutarate dehydrogenase), impaired oxidative metabolism, and increased activity of oxidative stress pathways, in which thiamine is a critical cofactor. Free thiamine in CSF has been reported to be lower in PD versus controls, suggesting central thiamine insufficiency despite normal plasma levels. Correcting functional thiamine deficits could improve neuronal bioenergetics.
30-40% / Mannitol
99% purity polyol. Investigated for anti-aggregation effects on α-synuclein and osmotic modulation; reduces protein buildup.supports fluid balance and may improve symptom management, making it a valuable adjunct to PD dietary support. Studies have found that orl mannitol binds to alpha-synuclein, preventing it from forming large, harmful clusters. As a result, animal studies showed significant improvement in their movement and coordination. mannitol scavenges reactive carbonyls and hydroxyl radicals that accelerate dopaminergic neuron death. In MPTP-lesioned mice, it restored glutathione levels and reduced key lipid peroxidation markers.
5-20% / Inulin
90% purity prebiotic fiber. Promotes microbiome balance and short-chain fatty acid production, linked to reduced neuroinflammation. Animal models of PD demonstrate that inulin supplementation can reduce neuroinflammation, protect dopamine-producing neurons, and improve motor function. Inulin SCFAs (short-chain fatty acids) improve glucose handling and strengthen gut tight junctions, which may stabilize levodopa uptake and smooth OFF periods. Inulin supplementation preserves hepatic glutathione, potentially buffering oxidative stress associated with chronic dopaminergic therapy. This purified form supports bowel regularity and gut–brain axis health, offering benefits for constipation and overall well-being in patients with
Core Synergies
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Marula Oil + Mannitol: Reduce protein aggregation (preclinical models show reduced α-synuclein)
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Marula Oil + Inulin: Enhanced gut microbiome support via fiber-lipid interactions
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Phosphatidylcholine + Marula Oil: High-confidence membrane repair and neuronal lipid stabilization
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B1 + All ingredients: Boosts thiamine-dependent enzymes for synergistic oxidative stress mitigation
PD Balance 2
11g daily with food | Antioxidants & Protein Clearance
(includes TUDCA capsules)
This pouch features lyophilized marula fruit for nutrient-dense antioxidant delivery. TUDCA is provided as capsules (500 mg, taken with Balance 2) due to its bitterness, but remains integral to the formula's neuroprotective synergy. It targets protein aggregation, energy failure, and lysosomal dysfunction.
70-90% / Lyophilized Marula Fruit & Peel extract powder
100% Organic, High-Dose Vitamin C, Polyphenols, and Minerals. Freeze-dried to preserve bioactives. Protects dopamine neurons through oxidative stress and reduces inflammation. Supports cellular resilience and overall vitality in Parkinson’s disease. Marula polyphenols promote the growth of beneficial bacteria (e.g., bifidobacteria) while suppressing pro-inflammatory bacteria. A balanced microbiome is linked to better bowel regularity and may even impact brain inflammation via the “gut-brain axis,” a topic increasingly being studied in Parkinson’s disease. Its organic status and purity support consistent anti-inflammatory and neuroprotective benefits.
1-3% / Salidroside
(1~3%) Sourced from Rhodiola with 99% purity to ensure potent mitochondrial and stress-response support. In PD models, it protects dopamine-producing cells by acting as an antioxidant and reducing inflammation. The purified compound enhances cellular repair mechanisms, offering potential benefits for energy and neuronal stability.
1-5% / Nicotinamide Riboside (NR)
(1~5%) A NAD+ precursor with high purity (99.58%) for bioenergetic support. For PD patients, it boosts cellular NAD+ levels and enhances mitochondrial function. The purified ingredient activates repair pathways and reduces inflammation.
1-2% / Ambroxol
99.6% purity. Enhances GCase activity for lysosomal function; reduces α-synuclein accumulation and supports neuronal health. Note: May not be available as supplement in some regions. Ambroxol is a mucolytic expectorant and has been available on the market in more than 50 countries for over 30 years. Ambroxol acts as a chaperone for GCase, facilitating effective trafficking from the ER and Golgi system to the lysosome. Importantly, ambroxol can be administered orally and crosses the blood-brain barrier. Oral ambroxol has also been demonstrated to increase GCase levels in non-human primates and in humans. These results support the potential of ambroxol as a disease-modifying treatment for synucleinopathies, such as PD. Studies with ambroxol in humans so far showed that ambroxol can be safely given in those higher dosages for a longer period. Please Note: may not be available at your region.
1-2% / Hydroxytyrosol (HXT)
(1~2%) An olive polyphenol standardized to high purity (20.12%) for potent antioxidant activity and inflammatory signaling support. It scavenges reactive species in neural tissue and modulates neuroinflammatory tone to benefit PD. The purified extract enhances mitochondrial stability and prevents protein clumping.
0.5-2% / Oleuropein
leuropein tackles several of the root problems in Parkinson’ protein clumping, free radicals build-up, energy failure, and inflammation - all at once. So far, the evidence is strong in lab and animal studies and points to real movement improvements. Adding olive-rich foods or a standardized supplement like oleuropein (with medical guidance) could provide an extra layer of neuron protectio
3-6% / N-Acetyl-Cysteine (NAC)
3~6%) This glutathione precursor is formulated at 99% purity for optimal antioxidant capacity and redox balance. For PD patients, it rebuilds glutathione reserves and quiets neuroinflammation, protecting dopamine neurons. The pure form supports mitochondrial function and brain chemical balance, helping reduce oxidative stress.
1-4% Phosphatidylserine (PS)
Phosphatidylserine is a safe, well-studied phospholipid that consistently improves mood and certain cognitive domains in Parkinson’s disease, with plausible mechanistic links to dopamine signalling and membrane health. The proposed reasons for these benefits include PS's role in supporting brain cell membrane health, enhancing dopamine signaling, and reducing neuroinflammation by lowers pro-inflammatory cytokines.
0.5-3% / Ubiquinol-10 (CoQ10)
(0.5~3%) The reduced form of CoQ10 is included with 98% purity, supporting electron transport and energy production. In PD, it enhances cellular energy and combats oxidative stress, protecting dopamine-producing cells. Chronic inflammation is believed to worsen brain cell loss in Parkinson’s. Ubiquinol-10 can help calm this inflammation, providing a healthier environment for nerve cells. The high-purity formulation guarantees effective antioxidant defense and mitochondrial support.
500mg /TUDCA - Tauroursodeoxycholic acid (Capsule)
Capsules, (3~6%). This bile-acid derivative is produced with high purity (99.8%) for endoplasmic reticulum stress modulation and proteostasis in PD models. It protects dopamine neurons by shielding them from apoptosis and by fighting inflammation, and is integrated into Balance 2 for its cryoprotective benefits. The high-purity, vegan form ensures consistent support for cellular energy systems and toxic protein reduction, with capsules used solely to mask bitterness without altering its core role in the formula.
Core Synergies
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Marula Fruit + HXT + Oleuropein: High-confidence oxidative stress reduction via polyphenol synergy
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NAC + TUDCA: NAC's glutathione support pairs with TUDCA's mitochondrial integrity for apoptosis prevention
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CoQ10 + Nicotinamide Riboside: Pro-energy shift via ATP and NAD+ boosting for mitochondrial recovery
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Ambroxol + TUDCA: Lysosomal enhancement and proteostasis for α-synuclein clearance